Discovery of Electrophiles and Profiling of Enzyme Cofactors

Reverse‐polarity activity‐based protein profiling (RP‐ABPP) is a chemical proteomics approach that uses nucleophilic probes amenable to “click” chemistry deployed into living cells in culture to capture, immunoprecipitate, and identify protein‐bound electrophiles. RP‐ABPP is used to characterize the...

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Detalles Bibliográficos
Autores principales: Dettling, Suzanne E., Ahmadi, Mina, Lin, Zongtao, He, Lin, Matthews, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285064/
https://www.ncbi.nlm.nih.gov/pubmed/33197155
http://dx.doi.org/10.1002/cpch.86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285064/
https://www.ncbi.nlm.nih.gov/pubmed/33197155
http://dx.doi.org/10.1002/cpch.86

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