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Discovery of Electrophiles and Profiling of Enzyme Cofactors
Reverse‐polarity activity‐based protein profiling (RP‐ABPP) is a chemical proteomics approach that uses nucleophilic probes amenable to “click” chemistry deployed into living cells in culture to capture, immunoprecipitate, and identify protein‐bound electrophiles. RP‐ABPP is used to characterize the...
Autores principales: | Dettling, Suzanne E., Ahmadi, Mina, Lin, Zongtao, He, Lin, Matthews, Megan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285064/ https://www.ncbi.nlm.nih.gov/pubmed/33197155 http://dx.doi.org/10.1002/cpch.86 |
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