Cargando…

Phosphodiesterase inhibitors roflumilast and vardenafil prevent sleep deprivation‐induced deficits in spatial pattern separation

Sleep deprivation (SD) is known to impair hippocampus‐dependent memory processes, in part by stimulating the phosphodiesterase (PDE) activity. In the present study, we assessed in mice whether SD also affects spatial pattern separation, a cognitive process that specifically requires the dentate gyru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heckman, Pim R. A., Roig Kuhn, Femke, Raven, Frank, Bolsius, Youri G., Prickaerts, Jos, Meerlo, Peter, Havekes, Robbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285343/ https://www.ncbi.nlm.nih.gov/pubmed/32056276 http://dx.doi.org/10.1002/syn.22150

Ejemplares similares

Sleep deprivation reduces the density of individual spine subtypes in a branch‐specific fashion in CA1 neurons
por: Bolsius, Youri G., et al.
Publicado: (2021)

Sleep deprivation‐induced impairment of memory consolidation is not mediated by glucocorticoid stress hormones
por: Raven, Frank, et al.
Publicado: (2019)

A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota
por: El Aidy, Sahar, et al.
Publicado: (2019)

Elucidating the role of protein synthesis in hippocampus‐dependent memory consolidation across the day and night
por: Raven, Frank, et al.
Publicado: (2020)

Acute administration of roflumilast enhances sensory gating in healthy young humans in a randomized trial
por: Heckman, Pim R. A., et al.
Publicado: (2017)

Preliminary evidence for the phosphodiesterase type-4 inhibitor, roflumilast, in ameliorating cognitive flexibility deficits in patients with schizophrenia
por: Livingston, Nicholas R, et al.
Publicado: (2021)

Roflumilast: first phosphodiesterase 4 inhibitor approved for treatment of COPD
por: Giembycz, Mark A, et al.
Publicado: (2010)

Phosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical Implications
por: Heckman, Pim R. A., et al.
Publicado: (2016)

Phosphodiesterase Inhibitors Sildenafil and Vardenafil Reduce Zebrafish Rod Photoreceptor Outer Segment Shedding
por: Campbell, Leah J., et al.
Publicado: (2017)

The Phosphodiesterase-5 Inhibitor Vardenafil Is a Potent Inhibitor of ABCB1/P-Glycoprotein Transporter
por: Ding, Pei-Rong, et al.
Publicado: (2011)

Roflumilast, a Novel Phosphodiesterase 4 Inhibitor, for COPD Patients with a History of Exacerbations
por: Field, Stephen K.
Publicado: (2011)

Roflumilast, a phosphodiesterase-4 inhibitor, induces phagocytic activity in Greek COPD patients
por: Porpodis, Konstantinos, et al.
Publicado: (2015)

Characterization of Resveratrol, Oxyresveratrol, Piceatannol and Roflumilast as Modulators of Phosphodiesterase Activity. Study of Yeast Lifespan
por: Matencio, Adrián, et al.
Publicado: (2020)

Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca(2+)-channel
por: Imam, Faisal, et al.
Publicado: (2020)

Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1
por: Havekes, Robbert, et al.
Publicado: (2016)

Erratum for “Roflumilast, a Novel Phosphodiesterase 4 Inhibitor, for COPD Patients with a History of Exacerbations”
Publicado: (2012)

Roflumilast, a type of phosphodiesterase 4 inhibitor, can reduce intestinal injury caused by sepsis
por: Zhang, Zhongyuan, et al.
Publicado: (2021)

Phosphodiesterase 5 (PDE-5) inhibitors (sildenafil, tadalafil, and vardenafil) effects on esophageal motility: a systematic review
por: Shafiee, Arman, et al.
Publicado: (2023)

The contribution of Parkin, PINK1 and DJ‐1 genes to selective neuronal degeneration in Parkinson's disease
por: van der Vlag, Marc, et al.
Publicado: (2020)

The Selective Phosphodiesterase 4 Inhibitor Roflumilast and Phosphodiesterase 3/4 Inhibitor Pumafentrine Reduce Clinical Score and TNF Expression in Experimental Colitis in Mice
por: Rieder, Florian, et al.
Publicado: (2013)

Improvement in duration of erection following phosphodiesterase type 5 inhibitor therapy with vardenafil in men with erectile dysfunction: the ENDURANCE study
por: Rosenberg, M T, et al.
Publicado: (2009)

Patient preference and satisfaction in erectile dysfunction therapy: a comparison of the three phosphodiesterase-5 inhibitors sildenafil, vardenafil and tadalafil
por: Raheem, Amr Abdel, et al.
Publicado: (2009)

Roflumilast, a Phosphodiesterases-4 (PDE4) Inhibitor, Alleviates Sepsis-induced Acute Kidney Injury
por: Xu, Xingkai, et al.
Publicado: (2020)

Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase‐5A inhibitor vardenafil in rats with type 2 diabetes
por: Mátyás, Csaba, et al.
Publicado: (2016)

Proniosomal Gel-Loaded Phosphodiesterase Inhibitors (Sildenafil, Vardenafil, and Tadalafil): Prospects for Topical Penile Therapy of Tadalafil for Treatment of Erectile Dysfunction
por: Mohamed, Soad A., et al.
Publicado: (2023)

Isolation and identification of a novel vardenafil analogue, propoxy-vardenafil, found as an adulterant in a health supplement
por: Sun, Jian, et al.
Publicado: (2023)

Translational Issues with the Development of Cognition Enhancing Drugs
por: Blokland, Arjan, et al.
Publicado: (2014)

Selective phosphodiesterase inhibitors: a promising target for cognition enhancement
por: Reneerkens, Olga A. H., et al.
Publicado: (2008)

The Phosphodiesterase 4 Inhibitor Roflumilast Protects against Cigarette Smoke Extract-Induced Mitophagy-Dependent Cell Death in Epithelial Cells
por: Kyung, Sun Young, et al.
Publicado: (2018)

An experimental medicine study of the phosphodiesterase-4 inhibitor, roflumilast, on working memory-related brain activity and episodic memory in schizophrenia patients
por: Gilleen, James, et al.
Publicado: (2018)

Cofilin overactivation improves hippocampus-dependent short-term memory
por: Raven, Frank, et al.
Publicado: (2023)

Separation and structural elucidation of a novel vardenafil analogue as an adulterant in a natural health care dietary supplement
por: Li, Chunzheng, et al.
Publicado: (2023)

Neuroinflammation in Ischemic Stroke: Inhibition of cAMP-Specific Phosphodiesterases (PDEs) to the Rescue
por: Ponsaerts, Laura, et al.
Publicado: (2021)

Vardenafil for the treatment of erectile dysfunction: an overview of the clinical evidence
por: Morales, Antonio Martín, et al.
Publicado: (2009)

Vardenafil Activity in Lung Fibrosis and In Vitro Synergy with Nintedanib
por: Bourne, Michael H., et al.
Publicado: (2021)

Phosphodiesterase-4 Inhibitor Roflumilast-Mediated Protective Effect in Sepsis-Induced Late-Phase Event of Acute Kidney Injury: A Narrative Review
por: Kazmi, Imran, et al.
Publicado: (2022)

Phosphodiesterase 4 inhibition after retrieval switches the memory fate favoring extinction instead of reconsolidation
por: Machado Batista Sohn, Jeferson, et al.
Publicado: (2023)

Roflumilast in COPD: a Brazilian perspective
por: Stirbulov, Roberto, et al.
Publicado: (2015)

Can roflumilast, a phosphodiesterase-4 inhibitor, improve clinical outcomes in patients with moderate-to-severe chronic obstructive pulmonary disease? A meta-analysis
por: Luo, Jian, et al.
Publicado: (2016)

Vardenafil como tratamiento en la disfunción eréctil : revisión bibliográfica
por: Rasgado Díaz, Fernando
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_conkelc40tdbplba4931ccbkqv