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Metformin in nucleus accumbens core reduces cue‐induced cocaine seeking in male and female rats

This study investigated the potential therapeutic effects of the FDA‐approved drug metformin on cue‐induced reinstatement of cocaine seeking. Metformin (dimethyl‐biguanide) is a first‐line treatment for type II diabetes that, among other mechanisms, is involved in the activation of adenosine monopho...

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Detalles Bibliográficos
Autores principales: Chan, Amy, Willard, Alexis, Mulloy, Sarah, Ibrahim, Noor, Sciaccotta, Allegra, Schonfeld, Mark, Spencer, Sade M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285471/
https://www.ncbi.nlm.nih.gov/pubmed/35470560
http://dx.doi.org/10.1111/adb.13165