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A robust, accurate, sensitive LC–MS/MS method to measure indoxyl sulfate, validated for plasma and kidney cells

Proximal tubular damage is an important prognostic determinant in various chronic kidney diseases (CKDs). Currently available diagnostic methods do not allow for early disease detection and are neither efficient. Indoxyl sulfate (IS) is an endogenous metabolite and protein‐bound uremic toxin that is...

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Detalles Bibliográficos
Autores principales: Ahmed, Sabbir, Sparidans, Rolf W., Lu, Jingyi, Mihaila, Silvia M., Gerritsen, Karin G. F., Masereeuw, Rosalinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285569/
https://www.ncbi.nlm.nih.gov/pubmed/34978088
http://dx.doi.org/10.1002/bmc.5307