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A robust, accurate, sensitive LC–MS/MS method to measure indoxyl sulfate, validated for plasma and kidney cells
Proximal tubular damage is an important prognostic determinant in various chronic kidney diseases (CKDs). Currently available diagnostic methods do not allow for early disease detection and are neither efficient. Indoxyl sulfate (IS) is an endogenous metabolite and protein‐bound uremic toxin that is...
Autores principales: | Ahmed, Sabbir, Sparidans, Rolf W., Lu, Jingyi, Mihaila, Silvia M., Gerritsen, Karin G. F., Masereeuw, Rosalinde |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285569/ https://www.ncbi.nlm.nih.gov/pubmed/34978088 http://dx.doi.org/10.1002/bmc.5307 |
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