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Particle‐based analysis elucidates the real retention capacities of virus filters and enables optimal virus clearance study design with evaluation systems of diverse virological characteristics

In virus clearance study (VCS) design, the amount of virus loaded onto the virus filters (VF) must be carefully controlled. A large amount of virus is required to demonstrate sufficient virus removal capability; however, too high a viral load causes virus breakthrough and reduces log reduction value...

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Detalles Bibliográficos
Autores principales: Kayukawa, Taiki, Yanagibashi, Akiyo, Hongo‐Hirasaki, Tomoko, Yanagida, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285584/
https://www.ncbi.nlm.nih.gov/pubmed/35064964
http://dx.doi.org/10.1002/btpr.3237