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An optimized MALDI MSI protocol for spatial detection of tryptic peptides in fresh frozen prostate tissue

MALDI MS imaging (MSI) is a powerful analytical tool for spatial peptide detection in heterogeneous tissues. Proper sample preparation is crucial to achieve high quality, reproducible measurements. Here we developed an optimized protocol for spatially resolved proteolytic peptide detection with MALD...

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Detalles Bibliográficos
Autores principales: Høiem, Therese S., Andersen, Maria K., Martin‐Lorenzo, Marta, Longuespée, Rémi, Claes, Britt S.R., Nordborg, Anna, Dewez, Frédéric, Balluff, Benjamin, Giampà, Marco, Sharma, Animesh, Hagen, Lars, Heeren, Ron M.A., Bathen, Tone F., Giskeødegård, Guro F., Krossa, Sebastian, Tessem, May‐Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285595/
https://www.ncbi.nlm.nih.gov/pubmed/35170848
http://dx.doi.org/10.1002/pmic.202100223