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An optimized MALDI MSI protocol for spatial detection of tryptic peptides in fresh frozen prostate tissue
MALDI MS imaging (MSI) is a powerful analytical tool for spatial peptide detection in heterogeneous tissues. Proper sample preparation is crucial to achieve high quality, reproducible measurements. Here we developed an optimized protocol for spatially resolved proteolytic peptide detection with MALD...
Autores principales: | Høiem, Therese S., Andersen, Maria K., Martin‐Lorenzo, Marta, Longuespée, Rémi, Claes, Britt S.R., Nordborg, Anna, Dewez, Frédéric, Balluff, Benjamin, Giampà, Marco, Sharma, Animesh, Hagen, Lars, Heeren, Ron M.A., Bathen, Tone F., Giskeødegård, Guro F., Krossa, Sebastian, Tessem, May‐Britt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285595/ https://www.ncbi.nlm.nih.gov/pubmed/35170848 http://dx.doi.org/10.1002/pmic.202100223 |
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