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Flavan‐3‐ol Microbial Metabolites Modulate Proteolysis in Neuronal Cells Reducing Amyloid‐beta (1‐42) Levels
INTRODUCTION: Alzheimer's disease (AD) is a progressive neurodegeneration characterized by extensive protein aggregation and deposition in the brain, associated with defective proteasomal and autophagic‐lysosomal proteolytic pathways. Since current drugs can only reduce specific symptoms, the i...
Autores principales: | Cecarini, Valentina, Cuccioloni, Massimiliano, Zheng, Yadong, Bonfili, Laura, Gong, Chunmei, Angeletti, Mauro, Mena, Pedro, Del Rio, Daniele, Eleuteri, Anna Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285603/ https://www.ncbi.nlm.nih.gov/pubmed/34318994 http://dx.doi.org/10.1002/mnfr.202100380 |
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