Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitis

Omaveloxolone is a potent activator of Nrf2, a master transcriptional regulator of a multitude of cytoprotective functions, including antioxidative, anti‐inflammatory, and mitochondrial bioenergetic effects. Some of the most potent known effects of Nrf2 involve hepatoprotective functions. The purpos...

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Detalles Bibliográficos
Autores principales: Reisman, Scott A., Ferguson, Deborah A., Lee, Chun‐Yue I., Proksch, Joel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285621/
https://www.ncbi.nlm.nih.gov/pubmed/32410268
http://dx.doi.org/10.1002/jbt.22526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285621/
https://www.ncbi.nlm.nih.gov/pubmed/32410268
http://dx.doi.org/10.1002/jbt.22526

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