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Influence of eight ABCB1 polymorphisms on antidepressant response in a prospective cohort of treatment‐free Russian patients with moderate or severe depression: An explorative psychopharmacological study with naturalistic design

BACKGROUND: Many antidepressants are substrates of P‐glycoprotein, an efflux transporter in the blood‐brain‐barrier encoded by the ABCB1 gene. Genetic variations might influence the transport rate of antidepressants and hence their pharmacological effects. This study investigates the influence of ei...

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Detalles Bibliográficos
Autores principales: Geers, Lisanne M., Ochi, Taichi, Vyalova, Natalya M., Losenkov, Innokentiy S., Paderina, Diana Z., Pozhidaev, Ivan V., Simutkin, German G., Bokhan, Nikolay A., Wilffert, Bob, Touw, Daniël J., Loonen, Anton J.M., Ivanova, Svetlana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285790/
https://www.ncbi.nlm.nih.gov/pubmed/34788473
http://dx.doi.org/10.1002/hup.2826