PBK Model‐Based Prediction of Intestinal Microbial and Host Metabolism of Zearalenone and Consequences for its Estrogenicity

SCOPE: The aim of the present study is to develop physiologically‐based kinetic (PBK) models for rat and human that include intestinal microbial and hepatic metabolism of zearalenone (ZEN) in order to predict systemic concentrations of ZEN and to obtain insight in the contribution of metabolism by t...

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Detalles Bibliográficos
Autores principales: Mendez‐Catala, Diana M., Wang, Qianrui, Rietjens, Ivonne M.C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285883/
https://www.ncbi.nlm.nih.gov/pubmed/34648686
http://dx.doi.org/10.1002/mnfr.202100443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285883/
https://www.ncbi.nlm.nih.gov/pubmed/34648686
http://dx.doi.org/10.1002/mnfr.202100443

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