Cargando…

Base editing in bovine embryos reveals a species-specific role of SOX2 in regulation of pluripotency

The emergence of the first three lineages during development is orchestrated by a network of transcription factors, which are best characterized in mice. However, the role and regulation of these factors are not completely conserved in other mammals, including human and cattle. Here, we establish a...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Lei, Shi, Yan, Wang, Huanan, Wang, Zizengchen, Dang, Yanna, Li, Shuang, Wang, Shaohua, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286228/
https://www.ncbi.nlm.nih.gov/pubmed/35788719
http://dx.doi.org/10.1371/journal.pgen.1010307