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Base editing in bovine embryos reveals a species-specific role of SOX2 in regulation of pluripotency
The emergence of the first three lineages during development is orchestrated by a network of transcription factors, which are best characterized in mice. However, the role and regulation of these factors are not completely conserved in other mammals, including human and cattle. Here, we establish a...
Autores principales: | Luo, Lei, Shi, Yan, Wang, Huanan, Wang, Zizengchen, Dang, Yanna, Li, Shuang, Wang, Shaohua, Zhang, Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286228/ https://www.ncbi.nlm.nih.gov/pubmed/35788719 http://dx.doi.org/10.1371/journal.pgen.1010307 |
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