Cargando…

Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells

The limited development of broadly neutralizing antibodies (BnAbs) during HIV infection is classically attributed to an inadequate B-cell help brought by functionally impaired T follicular helper (Tfh) cells. However, the determinants of Tfh-cell functional impairment and the signals contributing to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Munoz, Olivia, Banga, Riddhima, Schelling, Rachel, Procopio, Francesco Andrea, Mastrangelo, Andrea, Nortier, Pauline, Ohmiti, Khalid, Daraspe, Jean, Cavassini, Matthias, Fenwick, Craig, Perez, Laurent, Perreau, Matthieu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286290/ https://www.ncbi.nlm.nih.gov/pubmed/35788752 http://dx.doi.org/10.1371/journal.ppat.1010673

Ejemplares similares

Host Molecule Incorporation into HIV Virions, Potential Influences in HIV Pathogenesis
por: Munoz, Olivia, et al.
Publicado: (2022)

Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement
por: Banga, Riddhima, et al.
Publicado: (2019)

In Vitro Reactivation of Replication-Competent and Infectious HIV-1 by Histone Deacetylase Inhibitors
por: Banga, Riddhima, et al.
Publicado: (2016)

Elite and posttreatment controllers, two facets of HIV control
por: Mastrangelo, Andrea, et al.
Publicado: (2022)

Blood CXCR3(+) CD4 T Cells Are Enriched in Inducible Replication Competent HIV in Aviremic Antiretroviral Therapy-Treated Individuals
por: Banga, Riddhima, et al.
Publicado: (2018)

CD32(+) and PD-1(+) Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals
por: Noto, Alessandra, et al.
Publicado: (2018)

T‐cell exhaustion in HIV infection
por: Fenwick, Craig, et al.
Publicado: (2019)

CD160-Associated CD8 T-Cell Functional Impairment Is Independent of PD-1 Expression
por: Viganò, Selena, et al.
Publicado: (2014)

PD-1 Controls Follicular T Helper Cell Positioning and Function
por: Shi, Jingwen, et al.
Publicado: (2018)

Inducible HIV-1 Reservoir Quantification: Clinical Relevance, Applications and Advancements of TILDA
por: Lungu, Cynthia, et al.
Publicado: (2021)

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
por: Perreau, Matthieu, et al.
Publicado: (2013)

Life of T Follicular Helper Cells
por: Suh, Woong-Kyung
Publicado: (2015)

In Situ Characterization of Follicular Helper CD4 T Cells Using Multiplexed Imaging
por: Ioannidou, Kalliopi, et al.
Publicado: (2021)

Retroviral Env Glycoprotein Trafficking and Incorporation into Virions
por: Murakami, Tsutomu
Publicado: (2012)

Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions
por: Ujike, Makoto, et al.
Publicado: (2015)

Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells
por: Ritvo, Paul-Gydéon, et al.
Publicado: (2019)

T follicular helper cells and T follicular regulatory cells in autoimmune diseases
por: Qi, Jingjing, et al.
Publicado: (2023)

Regulation of T follicular helper cells by ICOS
por: Hutloff, Andreas
Publicado: (2015)

Follicular helper T cell in immunity and autoimmunity
por: Mesquita, D., et al.
Publicado: (2016)

T Follicular Helper Cells in Autoimmune Disorders
por: Gensous, Noémie, et al.
Publicado: (2018)

Primary cutaneous T‐follicular helper lymphoma
por: Fenu, Elena M., et al.
Publicado: (2023)

The architecture of neoplastic follicles in follicular lymphoma; analysis of the relationship between the tumor and follicular helper T cells
por: Townsend, William, et al.
Publicado: (2020)

Follicular helper-T cells restore CD8(+)-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy
por: Niogret, Julie, et al.
Publicado: (2021)

Phenotype, effector function, and tissue localization of PD-1-expressing human follicular helper T cell subsets
por: Wang, Chuanwu, et al.
Publicado: (2011)

A new role for circulating T follicular helper cells in humoral response to anti-PD-1 therapy
por: Sánchez-Alonso, Santiago, et al.
Publicado: (2020)

CXCR5(+)PD-1(+) follicular helper CD8 T cells control B cell tolerance
por: Chen, Yuhong, et al.
Publicado: (2019)

T follicular helper cells: a potential therapeutic target in follicular lymphoma
por: Ochando, Jordi, et al.
Publicado: (2017)

T follicular helper and T follicular regulatory cells have different TCR specificity
por: Maceiras, Ana Raquel, et al.
Publicado: (2017)

Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases
por: Yoshitomi, Hiroyuki, et al.
Publicado: (2020)

Follicular helper T cells are required for systemic autoimmunity
por: Linterman, Michelle A., et al.
Publicado: (2009)

Follicular helper T Cells and the B cells they help
por: Poholek, A, et al.
Publicado: (2012)

The origins, function, and regulation of T follicular helper cells
por: Ma, Cindy S., et al.
Publicado: (2012)

MicroRNAs, T follicular helper cells and inflammaging
por: Hawkes, Jason E., et al.
Publicado: (2015)

T follicular helper cells in patients with acute schistosomiasis
por: Zhang, Yumei, et al.
Publicado: (2016)

Memory T Follicular Helper CD4 T Cells
por: Hale, J. Scott, et al.
Publicado: (2015)

Insights into the Role of Follicular Helper T Cells in Autoimmunity
por: Park, Hong-Jai, et al.
Publicado: (2014)

Regulation of T Follicular Helper Cells in Islet Autoimmunity
por: Serr, Isabelle, et al.
Publicado: (2018)

Follicular Helper T Cells in DiGeorge Syndrome
por: Klocperk, Adam, et al.
Publicado: (2018)

Follicular Helper T Cells in Systemic Lupus Erythematosus
por: Kim, Sun Jung, et al.
Publicado: (2018)

Effect of follicular helper T cells on the pathogenesis of asthma
por: Ma, Xiaojuan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_keu9o4ss4ldr4p042rv06l249o