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Multimechanistic Single-Entity Combinations for Chronic Pain Control: A Narrative Review

Atypical opioids such as tramadol, tapentadol, and cebranopadol combine two complementary mechanisms of action into a single molecule, creating novel analgesic agents. These are synthetic small molecules: cebranopadol is not yet market released; tramadol and tapentadol are commercially available and...

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Detalles Bibliográficos
Autores principales: Pergolizzi, Joseph, Magnusson, Peter, Coluzzi, Flaminia, Breve, Frank, LeQuang, Jo Ann K, Varrassi, Giustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286298/
https://www.ncbi.nlm.nih.gov/pubmed/35855248
http://dx.doi.org/10.7759/cureus.26000