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Multimechanistic Single-Entity Combinations for Chronic Pain Control: A Narrative Review

Atypical opioids such as tramadol, tapentadol, and cebranopadol combine two complementary mechanisms of action into a single molecule, creating novel analgesic agents. These are synthetic small molecules: cebranopadol is not yet market released; tramadol and tapentadol are commercially available and...

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Detalles Bibliográficos
Autores principales:	Pergolizzi, Joseph, Magnusson, Peter, Coluzzi, Flaminia, Breve, Frank, LeQuang, Jo Ann K, Varrassi, Giustino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cureus 2022
Materias:	Pain Management
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286298/ https://www.ncbi.nlm.nih.gov/pubmed/35855248 http://dx.doi.org/10.7759/cureus.26000

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