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Database search engines and target database features impinge upon the identification of post‐translationally cis‐spliced peptides in HLA class I immunopeptidomes

Unconventional epitopes presented by HLA class I complexes are emerging targets for T cell targeted immunotherapies. Their identification by mass spectrometry (MS) required development of novel methods to cope with the large number of theoretical candidates. Methods to identify post‐translationally...

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Detalles Bibliográficos
Autores principales: Mishto, Michele, Horokhovskyi, Yehor, Cormican, John A., Yang, Xiaoping, Lynham, Steven, Urlaub, Henning, Liepe, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286349/
https://www.ncbi.nlm.nih.gov/pubmed/35184383
http://dx.doi.org/10.1002/pmic.202100226