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Utility of progesterone receptor‐ires‐Cre to generate conditional knockout mice for uterine study

In mice, the conditional knockout strategy using the Cre‐loxP system is useful for various types of research. The Cre mouse line with progesterone receptor promoter (Pgr ( Cre )) has been widely used to produce specific uterine gene‐deficient mice, but in the Cre line, endogenous Pgr gene is replace...

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Detalles Bibliográficos
Autores principales: Namiki, Takafumi, Kamoshita, Maki, Kageyama, Atsuko, Terakawa, Jumpei, Ito, Junya, Kashiwazaki, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286405/
https://www.ncbi.nlm.nih.gov/pubmed/34402137
http://dx.doi.org/10.1111/asj.13615