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Platelet-derived growth factor-BB and white matter hyperintensity burden in APOE4 carriers

BACKGROUND: The apolipoprotein-e4 (APOE4) gene increases risk for developing late-onset Alzheimer's disease (AD) and has been linked to increased microvascular dysfunction, including pericyte degeneration and blood-brain barrier breakdown. Platelet-derived growth factor-BB (PDGF-BB) is a glycop...

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Detalles Bibliográficos
Autores principales: Kapoor, Arunima, Nation, Daniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286493/
https://www.ncbi.nlm.nih.gov/pubmed/35844252
http://dx.doi.org/10.1016/j.cccb.2022.100131