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Platelet-derived growth factor-BB and white matter hyperintensity burden in APOE4 carriers
BACKGROUND: The apolipoprotein-e4 (APOE4) gene increases risk for developing late-onset Alzheimer's disease (AD) and has been linked to increased microvascular dysfunction, including pericyte degeneration and blood-brain barrier breakdown. Platelet-derived growth factor-BB (PDGF-BB) is a glycop...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286493/ https://www.ncbi.nlm.nih.gov/pubmed/35844252 http://dx.doi.org/10.1016/j.cccb.2022.100131 |