Global protein dynamics as communication sensors in peptide synthetase domains

Biological activity is governed by the timely redistribution of molecular interactions, and static structural snapshots often appear insufficient to provide the molecular determinants that choreograph communication. This conundrum applies to multidomain enzymatic systems called nonribosomal peptide...

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Detalles Bibliográficos
Autores principales: Mishra, Subrata H., Kancherla, Aswani K., Marincin, Kenneth A., Bouvignies, Guillaume, Nerli, Santrupti, Sgourakis, Nikolaos, Dowling, Daniel P., Frueh, Dominique P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286511/
https://www.ncbi.nlm.nih.gov/pubmed/35857508
http://dx.doi.org/10.1126/sciadv.abn6549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286511/
https://www.ncbi.nlm.nih.gov/pubmed/35857508
http://dx.doi.org/10.1126/sciadv.abn6549

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