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Functional genomic analysis of epithelioid sarcoma reveals distinct proximal and distal subtype biology

BACKGROUND: Metastatic epithelioid sarcoma (EPS) remains a largely unmet clinical need in children, adolescents and young adults despite the advent of EZH2 inhibitor tazemetostat. METHODS: In order to realise consistently effective drug therapies, a functional genomics approach was used to identify...

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Detalles Bibliográficos
Autores principales: Rasmussen, Samuel V., Jin, Jia xiang, Bickford, Lissett R., Woods, Andrew D., Sahm, Felix, Crawford, Kenneth A., Nagamori, Kiyo, Goto, Hiroaki, Torres, Keila E., Sidoni, Angelo, Rudzinski, Erin R., Thway, Khin, Jones, Robin L., Ciulli, Alessio, Wright, Hollis, Lathara, Melvin, Srinivasa, Ganapati, Kannan, Kavya, Huang, Paul H., Grünewald, Thomas G. P., Berlow, Noah E., Keller, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286527/
https://www.ncbi.nlm.nih.gov/pubmed/35839307
http://dx.doi.org/10.1002/ctm2.961