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Chronic androgen excess in female mice does not impact luteinizing hormone pulse frequency or putative GABAergic inputs to GnRH neurons

Polycystic ovary syndrome (PCOS) is associated with androgen excess and, frequently, hyperactive pulsatile luteinizing hormone (LH) secretion. Although the origins of PCOS are unclear, evidence from pre‐clinical models implicates androgen signalling in the brain in the development of PCOS pathophysi...

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Detalles Bibliográficos
Autores principales: Coyle, Chris S., Prescott, Melanie, Handelsman, David J, Walters, Kirsty A., Campbell, Rebecca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286661/
https://www.ncbi.nlm.nih.gov/pubmed/35267218
http://dx.doi.org/10.1111/jne.13110