Microduplication of 16p11.2 locus Potentiates Hypertrophic Obesity in Association with Imbalanced Triglyceride Metabolism in White Adipose Tissue

SCOPE: Copy number variation (CNV) of 16p11.2 is a common genetic factor contributing to the etiology of abnormal weight status, while the underlying mechanism is not fully elucidated yet. METHODS AND RESULTS: The 16p11.2 CNV mouse model with microduplication of the 7Slx1b‐Sept1 region (dp/+) is eva...

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Detalles Bibliográficos
Autores principales: Wang, Dilong, Mai, Qiuyan, Yang, Xiuyan, Chi, Xinjin, Li, Ruohan, Jiang, Jian, Luo, Liang, Fang, Xiaoyi, Yun, Peng, Liang, Liyang, Yang, Guang, Song, Kun, Fang, Liang, Chen, Yun, Zhang, Ying, He, Yulong, Li, Ningning, Pan, Yihang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286681/
https://www.ncbi.nlm.nih.gov/pubmed/35072981
http://dx.doi.org/10.1002/mnfr.202100241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286681/
https://www.ncbi.nlm.nih.gov/pubmed/35072981
http://dx.doi.org/10.1002/mnfr.202100241

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