Nuclear pore blockade reveals HIV-1 completes reverse transcription and uncoating in the nucleus

Retroviral infection involves the reverse transcription of the viral RNA genome into DNA, which is subsequently integrated into the host cell genome. HIV-1 and other lentiviruses are able to mediate the infection of non-dividing cells through the ability of the capsid (CA) protein (1) to engage the...

Descripción completa

Detalles Bibliográficos
Autores principales: Dharan, Adarsh, Bachmann, Niklas, Talley, Sarah, Zwikelmaier, Virginia, Campbell, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286700/
https://www.ncbi.nlm.nih.gov/pubmed/32483230
http://dx.doi.org/10.1038/s41564-020-0735-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286700/
https://www.ncbi.nlm.nih.gov/pubmed/32483230
http://dx.doi.org/10.1038/s41564-020-0735-8

Ejemplares similares