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Nuclear pore blockade reveals HIV-1 completes reverse transcription and uncoating in the nucleus
Retroviral infection involves the reverse transcription of the viral RNA genome into DNA, which is subsequently integrated into the host cell genome. HIV-1 and other lentiviruses are able to mediate the infection of non-dividing cells through the ability of the capsid (CA) protein (1) to engage the...
Autores principales: | Dharan, Adarsh, Bachmann, Niklas, Talley, Sarah, Zwikelmaier, Virginia, Campbell, Edward M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286700/ https://www.ncbi.nlm.nih.gov/pubmed/32483230 http://dx.doi.org/10.1038/s41564-020-0735-8 |
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