Guide to development of compound files for PBPK modeling in the Simcyp population‐based simulator

The Simcyp Simulator is a software platform for population physiologically‐based pharmacokinetic (PBPK) modeling and simulation. It links in vitro data to in vivo absorption, distribution, metabolism, excretion and pharmacokinetic/pharmacodynamic outcomes to explore clinical scenarios and support dr...

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Detalles Bibliográficos
Autores principales: Ezuruike, Udoamaka, Zhang, Mian, Pansari, Amita, De Sousa Mendes, Mailys, Pan, Xian, Neuhoff, Sibylle, Gardner, Iain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Tutorials
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286711/
https://www.ncbi.nlm.nih.gov/pubmed/35344639
http://dx.doi.org/10.1002/psp4.12791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286711/
https://www.ncbi.nlm.nih.gov/pubmed/35344639
http://dx.doi.org/10.1002/psp4.12791

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