Quantitative systems pharmacology modeling provides insight into inter‐mouse variability of Anti‐CTLA4 response

Clinical responses of immuno‐oncology therapies are highly variable among patients. Similar response variability has been observed in syngeneic mouse models. Understanding of the variability in the mouse models may shed light on patient variability. Using a murine anti‐CTLA4 antibody as a case study...

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Detalles Bibliográficos
Autores principales: Qiao, Wenlian, Lin, Lin, Young, Carissa, Narula, Jatin, Hua, Fei, Matteson, Andrew, Hooper, Andrea, Gruenbaum, Lore, Betts, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286718/
https://www.ncbi.nlm.nih.gov/pubmed/35439371
http://dx.doi.org/10.1002/psp4.12800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286718/
https://www.ncbi.nlm.nih.gov/pubmed/35439371
http://dx.doi.org/10.1002/psp4.12800

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