Development and application of a pediatric mechanistic kidney model

Pediatric physiologically‐based pharmacokinetic (P‐PBPK) models have been used to predict age related changes in the pharmacokinetics (PKs) of renally cleared drugs mainly in relation to changes in glomerular filtration rate. With emerging data on ontogeny of renal transporters, mechanistic models o...

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Detalles Bibliográficos
Autores principales: Salem, Farzaneh, Small, Ben G., Johnson, Trevor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286721/
https://www.ncbi.nlm.nih.gov/pubmed/35506351
http://dx.doi.org/10.1002/psp4.12798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286721/
https://www.ncbi.nlm.nih.gov/pubmed/35506351
http://dx.doi.org/10.1002/psp4.12798

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