Age and diet shape the genetic architecture of body weight in diversity outbred mice

Understanding how genetic variation shapes a complex trait relies on accurately quantifying both the additive genetic and genotype–environment interaction effects in an age-dependent manner. We used a linear mixed model to quantify diet-dependent genetic contributions to body weight measured through...

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Detalles Bibliográficos
Autores principales: Wright, Kevin M, Deighan, Andrew G, Di Francesco, Andrea, Freund, Adam, Jojic, Vladimir, Churchill, Gary A, Raj, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286741/
https://www.ncbi.nlm.nih.gov/pubmed/35838135
http://dx.doi.org/10.7554/eLife.64329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286741/
https://www.ncbi.nlm.nih.gov/pubmed/35838135
http://dx.doi.org/10.7554/eLife.64329

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