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Sciatic nerve injury rebalances the hypothalamic–pituitary–adrenal axis in rats with persistent changes to their social behaviours

Increased glucocorticoids characterise acute pain responses, but not the chronic pain state, suggesting specific modifications to the hypothalamic–pituitary–adrenal (HPA)‐axis preventing the persistent nature of chronic pain from elevating basal glucocorticoid levels. Individuals with chronic pain m...

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Detalles Bibliográficos
Autores principales: Sosa, M. Karmina, Boorman, Damien C., Keay, Kevin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286784/
https://www.ncbi.nlm.nih.gov/pubmed/35487591
http://dx.doi.org/10.1111/jne.13131