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Effect of phosphodiesterase‐4 inhibitor rolipram on colonic hypermotility in water avoidance stress rat model

BACKGROUND: Phosphodiesterase (PDE) inhibition has been reported to play a role in regulating gut motility, but the evidence is insufficient, and the mechanism remains unknown. The aim of this study was to investigate the possible role of phosphodiesterase‐4 (PDE4) inhibitor rolipram in water avoida...

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Detalles Bibliográficos
Autores principales: Yuan, FangTing, Ren, HaiXia, Tan, Wei, Wang, Ying, Luo, HeSheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286810/
https://www.ncbi.nlm.nih.gov/pubmed/35037375
http://dx.doi.org/10.1111/nmo.14317