Celebrities in the heart, strangers in the pancreatic beta cell: Voltage‐gated potassium channels K(v)7.1 and K(v)11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes

Voltage‐gated potassium (K(v)) channels play an important role in the repolarization of a variety of excitable tissues, including in the cardiomyocyte and the pancreatic beta cell. Recently, individuals carrying loss‐of‐function (LoF) mutations in KCNQ1, encoding K(v)7.1, and KCNH2 (hERG), encoding...

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Detalles Bibliográficos
Autores principales: Lubberding, Anniek F., Juhl, Christian R., Skovhøj, Emil Z., Kanters, Jørgen K., Mandrup‐Poulsen, Thomas, Torekov, Signe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286829/
https://www.ncbi.nlm.nih.gov/pubmed/34990074
http://dx.doi.org/10.1111/apha.13781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286829/
https://www.ncbi.nlm.nih.gov/pubmed/34990074
http://dx.doi.org/10.1111/apha.13781

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