Cargando…

Celebrities in the heart, strangers in the pancreatic beta cell: Voltage‐gated potassium channels K(v)7.1 and K(v)11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes

Voltage‐gated potassium (K(v)) channels play an important role in the repolarization of a variety of excitable tissues, including in the cardiomyocyte and the pancreatic beta cell. Recently, individuals carrying loss‐of‐function (LoF) mutations in KCNQ1, encoding K(v)7.1, and KCNH2 (hERG), encoding...

Descripción completa

Detalles Bibliográficos
Autores principales: Lubberding, Anniek F., Juhl, Christian R., Skovhøj, Emil Z., Kanters, Jørgen K., Mandrup‐Poulsen, Thomas, Torekov, Signe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286829/
https://www.ncbi.nlm.nih.gov/pubmed/34990074
http://dx.doi.org/10.1111/apha.13781

Ejemplares similares