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Celebrities in the heart, strangers in the pancreatic beta cell: Voltage‐gated potassium channels K(v)7.1 and K(v)11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes
Voltage‐gated potassium (K(v)) channels play an important role in the repolarization of a variety of excitable tissues, including in the cardiomyocyte and the pancreatic beta cell. Recently, individuals carrying loss‐of‐function (LoF) mutations in KCNQ1, encoding K(v)7.1, and KCNH2 (hERG), encoding...
Autores principales: | Lubberding, Anniek F., Juhl, Christian R., Skovhøj, Emil Z., Kanters, Jørgen K., Mandrup‐Poulsen, Thomas, Torekov, Signe S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286829/ https://www.ncbi.nlm.nih.gov/pubmed/34990074 http://dx.doi.org/10.1111/apha.13781 |
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