Fate‐mapping of erythropoietin‐producing cells in mouse models of hypoxaemia and renal tissue remodelling reveals repeated recruitment and persistent functionality

AIM: Fibroblast‐like renal erythropoietin (Epo) producing (REP) cells of the corticomedullary border region “sense” a decrease in blood oxygen content following anaemia or hypoxaemia. Burst‐like transcription of Epo during tissue hypoxia is transient and is lost during fibrotic tissue remodelling, a...

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Detalles Bibliográficos
Autores principales: Dahl, Sophie L., Pfundstein, Svende, Hunkeler, Rico, Dong, Xingtong, Knöpfel, Thomas, Spielmann, Patrick, Scholz, Carsten C., Nolan, Karen A., Wenger, Roland H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Renal Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286872/
https://www.ncbi.nlm.nih.gov/pubmed/34982511
http://dx.doi.org/10.1111/apha.13768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286872/
https://www.ncbi.nlm.nih.gov/pubmed/34982511
http://dx.doi.org/10.1111/apha.13768

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