Ketamine Promotes LPS-Induced Pulmonary Autophagy and Reduces Apoptosis through the AMPK/mTOR Pathway

To explore the protective effect of ketamine on acute lung injury (ALI) in sepsis mice regarding the autophagy and apoptosis, lipopolysaccharide (LPS) was used to construct a sepsis-induced ALI model. In in vivo experiments, ketamine at a concentration of 20 mg/kg was injected before modeling. The s...

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Detalles Bibliográficos
Autores principales: Cao, Jianwei, Mai, Huiqiang, Chen, Yanfen, Yuan, Ruilin, Fang, Erbin, Liu, Meiling, Fu, Chunlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286940/
https://www.ncbi.nlm.nih.gov/pubmed/35854770
http://dx.doi.org/10.1155/2022/8713701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286940/
https://www.ncbi.nlm.nih.gov/pubmed/35854770
http://dx.doi.org/10.1155/2022/8713701

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