MANF Inhibits α-Synuclein Accumulation through Activation of Autophagic Pathways

Progressive accumulation of misfolded SNCA/α-synuclein is key to the pathology of Parkinson's disease (PD). Drugs aiming at degrading SNCA may be an efficient therapeutic strategy for PD. Our previous study showed that mesencephalic astrocyte-derived neurotrophic factor (MANF) facilitated the r...

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Detalles Bibliográficos
Autores principales: Zhang, Jing-Xing, Tong, Wei-Fang, Jiang, Ming, Zhou, Kai-Ge, Xiang, Xue-rui, He, Yi-jing, Zhang, Zhuo-yu, Guan, Qiang, Jin, Ling-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286947/
https://www.ncbi.nlm.nih.gov/pubmed/35847585
http://dx.doi.org/10.1155/2022/7925686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286947/
https://www.ncbi.nlm.nih.gov/pubmed/35847585
http://dx.doi.org/10.1155/2022/7925686

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