Tandem mass spectrometric sequence characterization of synthetic thymidine‐rich oligonucleotides

Tandem mass spectrometry (MS/MS) can provide direct and accurate sequence characterization of synthetic oligonucleotide drugs, including modified oligonucleotides. Multiple factors can affect oligonucleotide MS/MS sequencing, including the intrinsic properties of oligonucleotides (i.e., nucleotide c...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdullah, A. M., Sommers, Cynthia, Hawes, Jessica, Rodriguez, Jason D., Yang, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287059/
https://www.ncbi.nlm.nih.gov/pubmed/35347805
http://dx.doi.org/10.1002/jms.4819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287059/
https://www.ncbi.nlm.nih.gov/pubmed/35347805
http://dx.doi.org/10.1002/jms.4819

Ejemplares similares