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Tandem mass spectrometric sequence characterization of synthetic thymidine‐rich oligonucleotides

Tandem mass spectrometry (MS/MS) can provide direct and accurate sequence characterization of synthetic oligonucleotide drugs, including modified oligonucleotides. Multiple factors can affect oligonucleotide MS/MS sequencing, including the intrinsic properties of oligonucleotides (i.e., nucleotide c...

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Detalles Bibliográficos
Autores principales:	Abdullah, A. M., Sommers, Cynthia, Hawes, Jessica, Rodriguez, Jason D., Yang, Kui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287059/ https://www.ncbi.nlm.nih.gov/pubmed/35347805 http://dx.doi.org/10.1002/jms.4819

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