Epigenetic modifier SMCHD1 maintains a normal pool of long-term hematopoietic stem cells

SMCHD1 (structural maintenance of chromosomes hinge domain containing 1) is a noncanonical SMC protein that mediates long-range repressive chromatin structures. SMCHD1 is required for X chromosome inactivation in female cells and repression of imprinted and clustered autosomal genes, with SMCHD1 mut...

Descripción completa

Detalles Bibliográficos
Autores principales: Kinkel, Sarah A., Liu, Joy, Beck, Tamara, Breslin, Kelsey A., Iminitoff, Megan, Hickey, Peter, Blewitt, Marnie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287190/
https://www.ncbi.nlm.nih.gov/pubmed/35856023
http://dx.doi.org/10.1016/j.isci.2022.104684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287190/
https://www.ncbi.nlm.nih.gov/pubmed/35856023
http://dx.doi.org/10.1016/j.isci.2022.104684

Ejemplares similares