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Epigenetic modifier SMCHD1 maintains a normal pool of long-term hematopoietic stem cells

SMCHD1 (structural maintenance of chromosomes hinge domain containing 1) is a noncanonical SMC protein that mediates long-range repressive chromatin structures. SMCHD1 is required for X chromosome inactivation in female cells and repression of imprinted and clustered autosomal genes, with SMCHD1 mut...

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Detalles Bibliográficos
Autores principales:	Kinkel, Sarah A., Liu, Joy, Beck, Tamara, Breslin, Kelsey A., Iminitoff, Megan, Hickey, Peter, Blewitt, Marnie E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287190/ https://www.ncbi.nlm.nih.gov/pubmed/35856023 http://dx.doi.org/10.1016/j.isci.2022.104684

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