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Repeated ketamine anesthesia during neurodevelopment upregulates hippocampal activity and enhances drug reward in male mice

Early exposures to anesthetics can cause long-lasting changes in excitatory/inhibitory synaptic transmission (E/I imbalance), an important mechanism for neurodevelopmental disorders. Since E/I imbalance is also involved with addiction, we further investigated possible changes in addiction-related be...

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Detalles Bibliográficos
Autores principales: Cui, Jianchen, Ju, Xianshu, Lee, Yulim, Hong, Boohwi, Kang, Hyojin, Han, Kihoon, Shin, Won-Ho, Park, Jiho, Lee, Min Joung, Kim, Yoon Hee, Ko, Youngkwon, Heo, Jun Young, Chung, Woosuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287305/
https://www.ncbi.nlm.nih.gov/pubmed/35840630
http://dx.doi.org/10.1038/s42003-022-03667-4