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Inhibition of cell invasion and migration by targeting matrix metalloproteinase-9 expression via sirtuin 6 silencing in human breast cancer cells

Sirtuin 6 (SIRT6) regulation is involved in carcinogenesis. However, its role in breast cancer (BC) metastasis remains unclear. We investigated the effects of SIRT6 on protein kinase C activator- and cytokine-mediated cancer cell invasion and migration in MCF-7 and MDA-MB-231 cells and the associati...

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Detalles Bibliográficos
Autores principales: Hong, On-Yu, Jang, Hye-Yeon, Lee, Young-Rae, Jung, Sung Hoo, Youn, Hyun Jo, Kim, Jong-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287314/
https://www.ncbi.nlm.nih.gov/pubmed/35840633
http://dx.doi.org/10.1038/s41598-022-16405-x