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Applying fluorescent dye assays to discriminate Escherichia coli chlorhexidine resistance phenotypes from porin and mlaA deletions and efflux pumps

Bacterial resistance to the antiseptic chlorhexidine (CHX), is a growing problem, recently shown to be caused by deleterious mutations to the phospholipid transport system component (mlaA) as well as efflux pump overexpression. Comparisons of CHX resistance mechanisms, such as porin deletions (ompCF...

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Detalles Bibliográficos
Autores principales: Gregorchuk, Branden S. J., Reimer, Shelby L., Slipski, Carmine J., Milner, Kieran A., Hiebert, Shannon L., Beniac, Daniel R., Booth, Timothy F., Zhanel, George G., Bay, Denice C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287405/
https://www.ncbi.nlm.nih.gov/pubmed/35840757
http://dx.doi.org/10.1038/s41598-022-15775-6