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Externalized phosphatidylinositides on apoptotic cells are eat-me signals recognized by CD14

Apoptotic cells are rapidly engulfed and removed by phagocytes after displaying cell surface eat-me signals. Among many phospholipids, only phosphatidylserine (PS) is known to act as an eat-me signal on apoptotic cells. Using unbiased proteomics, we identified externalized phosphatidylinositides (PI...

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Detalles Bibliográficos
Autores principales: Kim, Ok-Hee, Kang, Geun-Hyung, Hur, June, Lee, Jinwook, Jung, YunJae, Hong, In-Sun, Lee, Hookeun, Seo, Seung-Yong, Lee, Dae Ho, Lee, Cheol Soon, Lee, In-Kyu, Bonner-Weir, Susan, Lee, Jongsoon, Park, Young Joo, Kim, Hyeonjin, Shoelson, Steven E., Oh, Byung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287416/
https://www.ncbi.nlm.nih.gov/pubmed/35017647
http://dx.doi.org/10.1038/s41418-022-00931-2