Dose–Exposure–Response Analysis of the Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone on UACR and eGFR: An Analysis from FIDELIO-DKD

BACKGROUND AND OBJECTIVE: Finerenone reduces the risk of kidney failure in patients with chronic kidney disease and type 2 diabetes. Changes in the urine albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) are surrogates for kidney failure. We performed dose–exposure–r...

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Detalles Bibliográficos
Autores principales: Goulooze, Sebastiaan Camiel, Heerspink, Hiddo J. L., van Noort, Martijn, Snelder, Nelleke, Brinker, Meike, Lippert, Joerg, Eissing, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287422/
https://www.ncbi.nlm.nih.gov/pubmed/35508594
http://dx.doi.org/10.1007/s40262-022-01124-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287422/
https://www.ncbi.nlm.nih.gov/pubmed/35508594
http://dx.doi.org/10.1007/s40262-022-01124-3

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