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Development of a universal antibiotic resistance screening reporter for improving efficiency of cytosine and adenine base editing
Base editing has emerged as a revolutionary technology for single nucleotide modifications. The cytosine and adenine base editors (CBEs and ABEs) have demonstrated great potential in clinical and fundamental research. However, screening and isolating target-edited cells remains challenging. In the c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287484/ https://www.ncbi.nlm.nih.gov/pubmed/35671823 http://dx.doi.org/10.1016/j.jbc.2022.102103 |