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Development of a universal antibiotic resistance screening reporter for improving efficiency of cytosine and adenine base editing

Base editing has emerged as a revolutionary technology for single nucleotide modifications. The cytosine and adenine base editors (CBEs and ABEs) have demonstrated great potential in clinical and fundamental research. However, screening and isolating target-edited cells remains challenging. In the c...

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Detalles Bibliográficos
Autores principales: Ma, Lixia, Xing, Jiani, Li, Qian, Zhang, Zhiying, Xu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287484/
https://www.ncbi.nlm.nih.gov/pubmed/35671823
http://dx.doi.org/10.1016/j.jbc.2022.102103