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Dissecting signaling hierarchies in the patterning of the mouse primitive streak using micropatterned EpiLC colonies

Embryo studies have established that the patterning of the mouse gastrula depends on a regulatory network in which the WNT, BMP, and NODAL signaling pathways cooperate, but aspects of their respective contributions remain unclear. Studying their impact on the spatial organization and developmental t...

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Detalles Bibliográficos
Autores principales: Plouhinec, Jean-Louis, Simon, Gaël, Vieira, Mathieu, Collignon, Jérôme, Sorre, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287665/
https://www.ncbi.nlm.nih.gov/pubmed/35714597
http://dx.doi.org/10.1016/j.stemcr.2022.05.009