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Fibroblast fate determination during cardiac reprogramming by remodeling of actin filaments

Fibroblasts can be reprogrammed into induced cardiomyocyte-like cells (iCMs) by forced expression of cardiogenic transcription factors. However, it remains unknown how fibroblasts adopt a cardiomyocyte (CM) fate during their spontaneous ongoing transdifferentiation toward myofibroblasts (MFs). By tr...

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Detalles Bibliográficos
Autores principales: Zhang, Zhentao, Zhang, Wenhui, Blakes, Robert, Sundby, Lauren J., Shi, Zengdun, Rockey, Don C., Ervasti, James M., Nam, Young-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287671/
https://www.ncbi.nlm.nih.gov/pubmed/35688153
http://dx.doi.org/10.1016/j.stemcr.2022.05.004